AutomedicationFrancoV1, Main, Exploration, bibRecord, 000299

Association between sleep disturbances, fear of hypoglycemia and psychological well-being in adults with type 1 diabetes mellitus, data from cross-sectional VARDIA study.

Identifieur interne : 000299 ( Main/Exploration ); précédent : 000298; suivant : 000300

Association between sleep disturbances, fear of hypoglycemia and psychological well-being in adults with type 1 diabetes mellitus, data from cross-sectional VARDIA study.

Auteurs : Valentine Suteau [France] ; Pierre-Jean Saulnier [France] ; Matthieu Wargny [France] ; Linda Gonder-Frederick [États-Unis] ; Elise Gand [France] ; Lucy Chaillous [France] ; Ingrid Allix [France] ; Séverine Dubois [France] ; Fabrice Bonnet [France] ; Anne-Marie Leguerrier [France] ; Gerard Fradet [France] ; Ingrid Delcourt Crespin [France] ; Véronique Kerlan [France] ; Didier Gouet [France] ; Caroline Perlemoine [France] ; Pierre-Henri Ducluzeau [France] ; Matthieu Pichelin [France] ; Stéphanie Ragot [France] ; Samy Hadjadj [France] ; Bertrand Cariou [France] ; Claire Briet [France]

Source :

Diabetes research and clinical practice [ 1872-8227 ] ; 2020.

RBID : pubmed:31866527

Descripteurs français

KwdFr :
- Adulte (MeSH), Adulte d'âge moyen (MeSH), Diabète de type 1 (complications), Diabète de type 1 (psychologie), Femelle (MeSH), Humains (MeSH), Hypoglycémie (sang), Mâle (MeSH), Peur (psychologie), Troubles de la veille et du sommeil (complications), Études transversales (MeSH).
MESH :
- psychologie : Diabète de type 1, Peur.
- sang : Diabète de type 1, Hypoglycémie, Troubles de la veille et du sommeil.
- Adulte, Adulte d'âge moyen, Femelle, Humains, Mâle, Études transversales.

English descriptors

KwdEn :
- Adult (MeSH), Cross-Sectional Studies (MeSH), Diabetes Mellitus, Type 1 (complications), Diabetes Mellitus, Type 1 (psychology), Fear (psychology), Female (MeSH), Humans (MeSH), Hypoglycemia (blood), Male (MeSH), Middle Aged (MeSH), Sleep Wake Disorders (complications).
MESH :
- blood : Hypoglycemia.
- complications : Diabetes Mellitus, Type 1, Sleep Wake Disorders.
- psychology : Diabetes Mellitus, Type 1, Fear.
- Adult, Cross-Sectional Studies, Female, Humans, Male, Middle Aged.

Abstract

AIM

To assess the relationship between sleep quality, fear of hypoglycemia, glycemic variability and psychological well-being in type 1 diabetes mellitus.

METHODS

Our data were provided by the VARDIA Study, a multicentric cross-sectional study conducted between June and December 2015. Sleep characteristics were assessed by the Pittsburgh Sleep Quality Index (PSQI). Fear of hypoglycemia and psychological well-being were measured with the Hypoglycemia Fear Survey version II (HFS-II) and the Hospital Anxiety and Depression Scale (HADS), respectively. Glycemic variability (GV) was determined using the CV of three 7-point self-monitoring blood glucose profiles and the mean amplitude of glycemic excursion (MAGE).

RESULTS

315 patients were eligible for PSQI questionnaire analysis: 54% women, mean age 47 ± 15, mean diabetes duration of 24 ± 13 years, HbA1c of 7.6 ± 0.9% (60 ± 7,5mmol/mol). Average PSQI score was 6.0 ± 3.3 and 59.8% of the patients had a PSQI score > 5. HFS-II score and HADS were significantly higher among "poor" sleepers (p < 0.0001) and PSQI score was positively associated with HADS (β = 0.22; 95% CI = 0.08;0.35). GV evaluated by CV or MAGE did not differ between "poor" and "good" sleepers (p = 0.28 and 0.54, respectively).

CONCLUSIONS

Adult patients with type 1 diabetes have sleep disturbances which correlate with psychological well-being. This study suggests that psychological management can be a target to improve sleep quality in adults with type 1 diabetes mellitus.

DOI: 10.1016/j.diabres.2019.107988
PubMed: 31866527

Affiliations:

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Le document en format XML

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<author><name sortKey="Dubois, Severine" sort="Dubois, Severine" uniqKey="Dubois S" first="Séverine" last="Dubois">Séverine Dubois</name>
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<author><name sortKey="Delcourt Crespin, Ingrid" sort="Delcourt Crespin, Ingrid" uniqKey="Delcourt Crespin I" first="Ingrid" last="Delcourt Crespin">Ingrid Delcourt Crespin</name>
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<author><name sortKey="Kerlan, Veronique" sort="Kerlan, Veronique" uniqKey="Kerlan V" first="Véronique" last="Kerlan">Véronique Kerlan</name>
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<country xml:lang="fr">France</country>
<wicri:regionArea>CHU Brest, Diabetes Department, Hôpital de La Cavale Blanche, Boulevard Tanguy Prigent, 29200 Brest</wicri:regionArea>
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<author><name sortKey="Perlemoine, Caroline" sort="Perlemoine, Caroline" uniqKey="Perlemoine C" first="Caroline" last="Perlemoine">Caroline Perlemoine</name>
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<country xml:lang="fr">France</country>
<wicri:regionArea>CH Bretagne Sud, Diabetes Department, 5 Avenue Choiseul, 56322 Lorient</wicri:regionArea>
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</placeName>
</affiliation>
</author>
<author><name sortKey="Ducluzeau, Pierre Henri" sort="Ducluzeau, Pierre Henri" uniqKey="Ducluzeau P" first="Pierre-Henri" last="Ducluzeau">Pierre-Henri Ducluzeau</name>
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<author><name sortKey="Pichelin, Matthieu" sort="Pichelin, Matthieu" uniqKey="Pichelin M" first="Matthieu" last="Pichelin">Matthieu Pichelin</name>
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<country xml:lang="fr">France</country>
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<affiliation wicri:level="3"><nlm:affiliation>Clinical Investigation Center CIC1402, CHU de Poitiers 2 rue de la Miletrie, 86000 Poitiers, France; CHU Poitiers, Diabetes Department, 2 rue de la Milétrie, CS 90577, 86000 Poitiers, France. Electronic address: samy.hadjadj@univ-nantes.fr.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Clinical Investigation Center CIC1402, CHU de Poitiers 2 rue de la Miletrie, 86000 Poitiers, France; CHU Poitiers, Diabetes Department, 2 rue de la Milétrie, CS 90577, 86000 Poitiers</wicri:regionArea>
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<country xml:lang="fr">France</country>
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<author><name sortKey="Briet, Claire" sort="Briet, Claire" uniqKey="Briet C" first="Claire" last="Briet">Claire Briet</name>
<affiliation wicri:level="4"><nlm:affiliation>Institut MITOVASC, UMR CNRS 6015, INSERM 1083, Université d'Angers, 3 rue Roger Amsler, 49100 Angers, France; Diabetes Department, CHU d'Angers, 4 rue Larrey, 49100 Angers, France. Electronic address: claire.briet@chu-angers.fr.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Institut MITOVASC, UMR CNRS 6015, INSERM 1083, Université d'Angers, 3 rue Roger Amsler, 49100 Angers, France; Diabetes Department, CHU d'Angers, 4 rue Larrey, 49100 Angers</wicri:regionArea>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Association between sleep disturbances, fear of hypoglycemia and psychological well-being in adults with type 1 diabetes mellitus, data from cross-sectional VARDIA study.</title>
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<country xml:lang="fr">France</country>
<wicri:regionArea>Clinical Investigation Center CIC1402, CHU de Poitiers 2 rue de la Miletrie, 86000 Poitiers, France; CHU Poitiers, Diabetes Department, 2 rue de la Milétrie, CS 90577, 86000 Poitiers</wicri:regionArea>
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<author><name sortKey="Wargny, Matthieu" sort="Wargny, Matthieu" uniqKey="Wargny M" first="Matthieu" last="Wargny">Matthieu Wargny</name>
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<country xml:lang="fr">France</country>
<wicri:regionArea>L'institut du thorax, CHU Nantes, INSERM CIC1413, Hôpital Nord Laennec Boulevard Jacques-Monod Saint-Herblain, 44093 Nantes Cedex 1</wicri:regionArea>
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</placeName>
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</author>
<author><name sortKey="Gonder Frederick, Linda" sort="Gonder Frederick, Linda" uniqKey="Gonder Frederick L" first="Linda" last="Gonder-Frederick">Linda Gonder-Frederick</name>
<affiliation wicri:level="2"><nlm:affiliation>University of Virginia, Charlottesville, VA, USA. Electronic address: LAG3G@hscmail.mcc.virginia.edu.</nlm:affiliation>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>University of Virginia, Charlottesville, VA</wicri:regionArea>
<placeName><region type="state">Virginie</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gand, Elise" sort="Gand, Elise" uniqKey="Gand E" first="Elise" last="Gand">Elise Gand</name>
<affiliation wicri:level="3"><nlm:affiliation>Clinical Investigation Center CIC1402, CHU de Poitiers 2 rue de la Miletrie, 86000 Poitiers, France. Electronic address: elise.gand@chu-poitiers.fr.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Clinical Investigation Center CIC1402, CHU de Poitiers 2 rue de la Miletrie, 86000 Poitiers</wicri:regionArea>
<placeName><region type="region" nuts="2">Nouvelle-Aquitaine</region>
<region type="old region" nuts="2">Poitou-Charentes</region>
<settlement type="city">Poitiers</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Chaillous, Lucy" sort="Chaillous, Lucy" uniqKey="Chaillous L" first="Lucy" last="Chaillous">Lucy Chaillous</name>
<affiliation wicri:level="3"><nlm:affiliation>L'institut du thorax, CHU Nantes, INSERM CIC1413, Hôpital Nord Laennec Boulevard Jacques-Monod Saint-Herblain, 44093 Nantes Cedex 1, France. Electronic address: lucy.chaillous@chu-nantes.fr.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>L'institut du thorax, CHU Nantes, INSERM CIC1413, Hôpital Nord Laennec Boulevard Jacques-Monod Saint-Herblain, 44093 Nantes Cedex 1</wicri:regionArea>
<placeName><region type="region" nuts="2">Pays de la Loire</region>
<settlement type="city">Nantes</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Allix, Ingrid" sort="Allix, Ingrid" uniqKey="Allix I" first="Ingrid" last="Allix">Ingrid Allix</name>
<affiliation wicri:level="3"><nlm:affiliation>Diabetes Department, CHU d'Angers, 4 rue Larrey, 49100 Angers, France. Electronic address: In.Allix@chu-angers.fr.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Diabetes Department, CHU d'Angers, 4 rue Larrey, 49100 Angers</wicri:regionArea>
<placeName><region type="region" nuts="2">Pays de la Loire</region>
<settlement type="city">Angers</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Dubois, Severine" sort="Dubois, Severine" uniqKey="Dubois S" first="Séverine" last="Dubois">Séverine Dubois</name>
<affiliation wicri:level="4"><nlm:affiliation>Diabetes Department, CHU d'Angers, 4 rue Larrey, 49100 Angers, France; INSERM U1063, Oxidative Stress and Metabolic Pathologies, Université d'Angers, CHU Angers, 4 Rue Larrey, 49933 Angers Cedex 9, France. Electronic address: Se.Dubois@chu-angers.fr.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Diabetes Department, CHU d'Angers, 4 rue Larrey, 49100 Angers, France; INSERM U1063, Oxidative Stress and Metabolic Pathologies, Université d'Angers, CHU Angers, 4 Rue Larrey, 49933 Angers Cedex 9</wicri:regionArea>
<placeName><region type="region" nuts="2">Pays de la Loire</region>
<settlement type="city">Angers</settlement>
</placeName>
<orgName type="university">Université d'Angers</orgName>
</affiliation>
</author>
<author><name sortKey="Bonnet, Fabrice" sort="Bonnet, Fabrice" uniqKey="Bonnet F" first="Fabrice" last="Bonnet">Fabrice Bonnet</name>
<affiliation wicri:level="3"><nlm:affiliation>CHU Rennes, Diabetes Department, 2 rue Henri Le Guilloux, 35033 Rennes Cedex 9, France. Electronic address: fabrice.bonnet@chu-rennes.fr.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>CHU Rennes, Diabetes Department, 2 rue Henri Le Guilloux, 35033 Rennes Cedex 9</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Rennes</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Leguerrier, Anne Marie" sort="Leguerrier, Anne Marie" uniqKey="Leguerrier A" first="Anne-Marie" last="Leguerrier">Anne-Marie Leguerrier</name>
<affiliation wicri:level="3"><nlm:affiliation>CHU Rennes, Diabetes Department, 2 rue Henri Le Guilloux, 35033 Rennes Cedex 9, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>CHU Rennes, Diabetes Department, 2 rue Henri Le Guilloux, 35033 Rennes Cedex 9</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Rennes</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Fradet, Gerard" sort="Fradet, Gerard" uniqKey="Fradet G" first="Gerard" last="Fradet">Gerard Fradet</name>
<affiliation wicri:level="3"><nlm:affiliation>CH Départemental Vendée, Boulevard Stéphane Moreau, 85000 La Roche-sur-Yon, France. Electronic address: gerard.fradet@chd-vendee.fr.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>CH Départemental Vendée, Boulevard Stéphane Moreau, 85000 La Roche-sur-Yon</wicri:regionArea>
<placeName><region type="region" nuts="2">Pays de la Loire</region>
<settlement type="city">La Roche-sur-Yon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Delcourt Crespin, Ingrid" sort="Delcourt Crespin, Ingrid" uniqKey="Delcourt Crespin I" first="Ingrid" last="Delcourt Crespin">Ingrid Delcourt Crespin</name>
<affiliation wicri:level="3"><nlm:affiliation>CH Départemental Vendée, Boulevard Stéphane Moreau, 85000 La Roche-sur-Yon, France. Electronic address: ingrid.delcourt-crespin@chd-vendee.fr.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>CH Départemental Vendée, Boulevard Stéphane Moreau, 85000 La Roche-sur-Yon</wicri:regionArea>
<placeName><region type="region" nuts="2">Pays de la Loire</region>
<settlement type="city">La Roche-sur-Yon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kerlan, Veronique" sort="Kerlan, Veronique" uniqKey="Kerlan V" first="Véronique" last="Kerlan">Véronique Kerlan</name>
<affiliation wicri:level="3"><nlm:affiliation>CHU Brest, Diabetes Department, Hôpital de La Cavale Blanche, Boulevard Tanguy Prigent, 29200 Brest, France. Electronic address: veronique.kerlan@chu-brest.fr.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>CHU Brest, Diabetes Department, Hôpital de La Cavale Blanche, Boulevard Tanguy Prigent, 29200 Brest</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Brest</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gouet, Didier" sort="Gouet, Didier" uniqKey="Gouet D" first="Didier" last="Gouet">Didier Gouet</name>
<affiliation wicri:level="3"><nlm:affiliation>CH La Rochelle, Diabetes Department, Rue du docteur Schweitzer, 17019 La Rochelle Cedex, France. Electronic address: didier.gouet@ch-larochelle.fr.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>CH La Rochelle, Diabetes Department, Rue du docteur Schweitzer, 17019 La Rochelle Cedex</wicri:regionArea>
<placeName><region type="region" nuts="2">Nouvelle-Aquitaine</region>
<region type="old region" nuts="2">Poitou-Charentes</region>
<settlement type="city">La Rochelle</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Perlemoine, Caroline" sort="Perlemoine, Caroline" uniqKey="Perlemoine C" first="Caroline" last="Perlemoine">Caroline Perlemoine</name>
<affiliation wicri:level="3"><nlm:affiliation>CH Bretagne Sud, Diabetes Department, 5 Avenue Choiseul, 56322 Lorient, France. Electronic address: c.perlemoine@ch-bretagne-sud.fr.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>CH Bretagne Sud, Diabetes Department, 5 Avenue Choiseul, 56322 Lorient</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Bretagne</region>
<settlement type="city">Lorient</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Ducluzeau, Pierre Henri" sort="Ducluzeau, Pierre Henri" uniqKey="Ducluzeau P" first="Pierre-Henri" last="Ducluzeau">Pierre-Henri Ducluzeau</name>
<affiliation wicri:level="3"><nlm:affiliation>CHU Tours, Diabetes Department, 2, boulevard Tonnellé, 37044 Tours cedex 9, France. Electronic address: ph.ducluzeau@chu-tours.fr.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>CHU Tours, Diabetes Department, 2, boulevard Tonnellé, 37044 Tours cedex 9</wicri:regionArea>
<placeName><region type="region" nuts="2">Centre-Val de Loire</region>
<region type="old region" nuts="2">Région Centre</region>
<settlement type="city">Tours</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Pichelin, Matthieu" sort="Pichelin, Matthieu" uniqKey="Pichelin M" first="Matthieu" last="Pichelin">Matthieu Pichelin</name>
<affiliation wicri:level="3"><nlm:affiliation>L'institut du thorax, CHU Nantes, INSERM CIC1413, Hôpital Nord Laennec Boulevard Jacques-Monod Saint-Herblain, 44093 Nantes Cedex 1, France. Electronic address: Matthieu.Pichelin@univ-nantes.fr.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>L'institut du thorax, CHU Nantes, INSERM CIC1413, Hôpital Nord Laennec Boulevard Jacques-Monod Saint-Herblain, 44093 Nantes Cedex 1</wicri:regionArea>
<placeName><region type="region" nuts="2">Pays de la Loire</region>
<settlement type="city">Nantes</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Ragot, Stephanie" sort="Ragot, Stephanie" uniqKey="Ragot S" first="Stéphanie" last="Ragot">Stéphanie Ragot</name>
<affiliation wicri:level="3"><nlm:affiliation>Clinical Investigation Center CIC1402, CHU de Poitiers 2 rue de la Miletrie, 86000 Poitiers, France. Electronic address: stephanie.ragot@univ-poitiers.fr.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Clinical Investigation Center CIC1402, CHU de Poitiers 2 rue de la Miletrie, 86000 Poitiers</wicri:regionArea>
<placeName><region type="region" nuts="2">Nouvelle-Aquitaine</region>
<region type="old region" nuts="2">Poitou-Charentes</region>
<settlement type="city">Poitiers</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Hadjadj, Samy" sort="Hadjadj, Samy" uniqKey="Hadjadj S" first="Samy" last="Hadjadj">Samy Hadjadj</name>
<affiliation wicri:level="3"><nlm:affiliation>Clinical Investigation Center CIC1402, CHU de Poitiers 2 rue de la Miletrie, 86000 Poitiers, France; CHU Poitiers, Diabetes Department, 2 rue de la Milétrie, CS 90577, 86000 Poitiers, France. Electronic address: samy.hadjadj@univ-nantes.fr.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Clinical Investigation Center CIC1402, CHU de Poitiers 2 rue de la Miletrie, 86000 Poitiers, France; CHU Poitiers, Diabetes Department, 2 rue de la Milétrie, CS 90577, 86000 Poitiers</wicri:regionArea>
<placeName><region type="region" nuts="2">Nouvelle-Aquitaine</region>
<region type="old region" nuts="2">Poitou-Charentes</region>
<settlement type="city">Poitiers</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Cariou, Bertrand" sort="Cariou, Bertrand" uniqKey="Cariou B" first="Bertrand" last="Cariou">Bertrand Cariou</name>
<affiliation wicri:level="3"><nlm:affiliation>L'institut du thorax, CHU Nantes, INSERM CIC1413, Hôpital Nord Laennec Boulevard Jacques-Monod Saint-Herblain, 44093 Nantes Cedex 1, France. Electronic address: bertrand.cariou@univ-nantes.fr.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>L'institut du thorax, CHU Nantes, INSERM CIC1413, Hôpital Nord Laennec Boulevard Jacques-Monod Saint-Herblain, 44093 Nantes Cedex 1</wicri:regionArea>
<placeName><region type="region" nuts="2">Pays de la Loire</region>
<settlement type="city">Nantes</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Briet, Claire" sort="Briet, Claire" uniqKey="Briet C" first="Claire" last="Briet">Claire Briet</name>
<affiliation wicri:level="4"><nlm:affiliation>Institut MITOVASC, UMR CNRS 6015, INSERM 1083, Université d'Angers, 3 rue Roger Amsler, 49100 Angers, France; Diabetes Department, CHU d'Angers, 4 rue Larrey, 49100 Angers, France. Electronic address: claire.briet@chu-angers.fr.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Institut MITOVASC, UMR CNRS 6015, INSERM 1083, Université d'Angers, 3 rue Roger Amsler, 49100 Angers, France; Diabetes Department, CHU d'Angers, 4 rue Larrey, 49100 Angers</wicri:regionArea>
<placeName><region type="region" nuts="2">Pays de la Loire</region>
<settlement type="city">Angers</settlement>
</placeName>
<orgName type="university">Université d'Angers</orgName>
</affiliation>
</author>
</analytic>
<series><title level="j">Diabetes research and clinical practice</title>
<idno type="eISSN">1872-8227</idno>
<imprint><date when="2020" type="published">2020</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult (MeSH)</term>
<term>Cross-Sectional Studies (MeSH)</term>
<term>Diabetes Mellitus, Type 1 (complications)</term>
<term>Diabetes Mellitus, Type 1 (psychology)</term>
<term>Fear (psychology)</term>
<term>Female (MeSH)</term>
<term>Humans (MeSH)</term>
<term>Hypoglycemia (blood)</term>
<term>Male (MeSH)</term>
<term>Middle Aged (MeSH)</term>
<term>Sleep Wake Disorders (complications)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte (MeSH)</term>
<term>Adulte d'âge moyen (MeSH)</term>
<term>Diabète de type 1 (complications)</term>
<term>Diabète de type 1 (psychologie)</term>
<term>Femelle (MeSH)</term>
<term>Humains (MeSH)</term>
<term>Hypoglycémie (sang)</term>
<term>Mâle (MeSH)</term>
<term>Peur (psychologie)</term>
<term>Troubles de la veille et du sommeil (complications)</term>
<term>Études transversales (MeSH)</term>
</keywords>
<keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Hypoglycemia</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Diabetes Mellitus, Type 1</term>
<term>Sleep Wake Disorders</term>
</keywords>
<keywords scheme="MESH" qualifier="psychologie" xml:lang="fr"><term>Diabète de type 1</term>
<term>Peur</term>
</keywords>
<keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Diabetes Mellitus, Type 1</term>
<term>Fear</term>
</keywords>
<keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Diabète de type 1</term>
<term>Hypoglycémie</term>
<term>Troubles de la veille et du sommeil</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Cross-Sectional Studies</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Femelle</term>
<term>Humains</term>
<term>Mâle</term>
<term>Études transversales</term>
</keywords>
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<front><div type="abstract" xml:lang="en"><p><b>AIM</b>
</p>
<p>To assess the relationship between sleep quality, fear of hypoglycemia, glycemic variability and psychological well-being in type 1 diabetes mellitus.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>METHODS</b>
</p>
<p>Our data were provided by the VARDIA Study, a multicentric cross-sectional study conducted between June and December 2015. Sleep characteristics were assessed by the Pittsburgh Sleep Quality Index (PSQI). Fear of hypoglycemia and psychological well-being were measured with the Hypoglycemia Fear Survey version II (HFS-II) and the Hospital Anxiety and Depression Scale (HADS), respectively. Glycemic variability (GV) was determined using the CV of three 7-point self-monitoring blood glucose profiles and the mean amplitude of glycemic excursion (MAGE).</p>
</div>
<div type="abstract" xml:lang="en"><p><b>RESULTS</b>
</p>
<p>315 patients were eligible for PSQI questionnaire analysis: 54% women, mean age 47 ± 15, mean diabetes duration of 24 ± 13 years, HbA1c of 7.6 ± 0.9% (60 ± 7,5mmol/mol). Average PSQI score was 6.0 ± 3.3 and 59.8% of the patients had a PSQI score > 5. HFS-II score and HADS were significantly higher among "poor" sleepers (p < 0.0001) and PSQI score was positively associated with HADS (β = 0.22; 95% CI = 0.08;0.35). GV evaluated by CV or MAGE did not differ between "poor" and "good" sleepers (p = 0.28 and 0.54, respectively).</p>
</div>
<div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b>
</p>
<p>Adult patients with type 1 diabetes have sleep disturbances which correlate with psychological well-being. This study suggests that psychological management can be a target to improve sleep quality in adults with type 1 diabetes mellitus.</p>
</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" IndexingMethod="Curated" Owner="NLM"><PMID Version="1">31866527</PMID>
<DateCompleted><Year>2020</Year>
<Month>06</Month>
<Day>03</Day>
</DateCompleted>
<DateRevised><Year>2020</Year>
<Month>06</Month>
<Day>03</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1872-8227</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>160</Volume>
<PubDate><Year>2020</Year>
<Month>Feb</Month>
</PubDate>
</JournalIssue>
<Title>Diabetes research and clinical practice</Title>
<ISOAbbreviation>Diabetes Res Clin Pract</ISOAbbreviation>
</Journal>
<ArticleTitle>Association between sleep disturbances, fear of hypoglycemia and psychological well-being in adults with type 1 diabetes mellitus, data from cross-sectional VARDIA study.</ArticleTitle>
<Pagination><MedlinePgn>107988</MedlinePgn>
</Pagination>
<ELocationID EIdType="pii" ValidYN="Y">S0168-8227(19)31315-4</ELocationID>
<ELocationID EIdType="doi" ValidYN="Y">10.1016/j.diabres.2019.107988</ELocationID>
<Abstract><AbstractText Label="AIM" NlmCategory="OBJECTIVE">To assess the relationship between sleep quality, fear of hypoglycemia, glycemic variability and psychological well-being in type 1 diabetes mellitus.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Our data were provided by the VARDIA Study, a multicentric cross-sectional study conducted between June and December 2015. Sleep characteristics were assessed by the Pittsburgh Sleep Quality Index (PSQI). Fear of hypoglycemia and psychological well-being were measured with the Hypoglycemia Fear Survey version II (HFS-II) and the Hospital Anxiety and Depression Scale (HADS), respectively. Glycemic variability (GV) was determined using the CV of three 7-point self-monitoring blood glucose profiles and the mean amplitude of glycemic excursion (MAGE).</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">315 patients were eligible for PSQI questionnaire analysis: 54% women, mean age 47 ± 15, mean diabetes duration of 24 ± 13 years, HbA1c of 7.6 ± 0.9% (60 ± 7,5mmol/mol). Average PSQI score was 6.0 ± 3.3 and 59.8% of the patients had a PSQI score > 5. HFS-II score and HADS were significantly higher among "poor" sleepers (p < 0.0001) and PSQI score was positively associated with HADS (β = 0.22; 95% CI = 0.08;0.35). GV evaluated by CV or MAGE did not differ between "poor" and "good" sleepers (p = 0.28 and 0.54, respectively).</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Adult patients with type 1 diabetes have sleep disturbances which correlate with psychological well-being. This study suggests that psychological management can be a target to improve sleep quality in adults with type 1 diabetes mellitus.</AbstractText>
<CopyrightInformation>Copyright © 2019 Elsevier B.V. All rights reserved.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Suteau</LastName>
<ForeName>Valentine</ForeName>
<Initials>V</Initials>
<AffiliationInfo><Affiliation>Institut MITOVASC, UMR CNRS 6015, INSERM 1083, Université d'Angers, 3 rue Roger Amsler, 49100 Angers, France; Diabetes Department, CHU d'Angers, 4 rue Larrey, 49100 Angers, France. Electronic address: valentine.courant@chu-angers.fr.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Saulnier</LastName>
<ForeName>Pierre-Jean</ForeName>
<Initials>PJ</Initials>
<AffiliationInfo><Affiliation>Clinical Investigation Center CIC1402, CHU de Poitiers 2 rue de la Miletrie, 86000 Poitiers, France; CHU Poitiers, Diabetes Department, 2 rue de la Milétrie, CS 90577, 86000 Poitiers, France. Electronic address: pierrejean.saulnier@gmail.com.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Wargny</LastName>
<ForeName>Matthieu</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>L'institut du thorax, CHU Nantes, INSERM CIC1413, Hôpital Nord Laennec Boulevard Jacques-Monod Saint-Herblain, 44093 Nantes Cedex 1, France. Electronic address: matthieu.wargny@chu-nantes.fr.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Gonder-Frederick</LastName>
<ForeName>Linda</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>University of Virginia, Charlottesville, VA, USA. Electronic address: LAG3G@hscmail.mcc.virginia.edu.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Gand</LastName>
<ForeName>Elise</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>Clinical Investigation Center CIC1402, CHU de Poitiers 2 rue de la Miletrie, 86000 Poitiers, France. Electronic address: elise.gand@chu-poitiers.fr.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Chaillous</LastName>
<ForeName>Lucy</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>L'institut du thorax, CHU Nantes, INSERM CIC1413, Hôpital Nord Laennec Boulevard Jacques-Monod Saint-Herblain, 44093 Nantes Cedex 1, France. Electronic address: lucy.chaillous@chu-nantes.fr.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Allix</LastName>
<ForeName>Ingrid</ForeName>
<Initials>I</Initials>
<AffiliationInfo><Affiliation>Diabetes Department, CHU d'Angers, 4 rue Larrey, 49100 Angers, France. Electronic address: In.Allix@chu-angers.fr.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Dubois</LastName>
<ForeName>Séverine</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Diabetes Department, CHU d'Angers, 4 rue Larrey, 49100 Angers, France; INSERM U1063, Oxidative Stress and Metabolic Pathologies, Université d'Angers, CHU Angers, 4 Rue Larrey, 49933 Angers Cedex 9, France. Electronic address: Se.Dubois@chu-angers.fr.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Bonnet</LastName>
<ForeName>Fabrice</ForeName>
<Initials>F</Initials>
<AffiliationInfo><Affiliation>CHU Rennes, Diabetes Department, 2 rue Henri Le Guilloux, 35033 Rennes Cedex 9, France. Electronic address: fabrice.bonnet@chu-rennes.fr.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Leguerrier</LastName>
<ForeName>Anne-Marie</ForeName>
<Initials>AM</Initials>
<AffiliationInfo><Affiliation>CHU Rennes, Diabetes Department, 2 rue Henri Le Guilloux, 35033 Rennes Cedex 9, France.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Fradet</LastName>
<ForeName>Gerard</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>CH Départemental Vendée, Boulevard Stéphane Moreau, 85000 La Roche-sur-Yon, France. Electronic address: gerard.fradet@chd-vendee.fr.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Delcourt Crespin</LastName>
<ForeName>Ingrid</ForeName>
<Initials>I</Initials>
<AffiliationInfo><Affiliation>CH Départemental Vendée, Boulevard Stéphane Moreau, 85000 La Roche-sur-Yon, France. Electronic address: ingrid.delcourt-crespin@chd-vendee.fr.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Kerlan</LastName>
<ForeName>Véronique</ForeName>
<Initials>V</Initials>
<AffiliationInfo><Affiliation>CHU Brest, Diabetes Department, Hôpital de La Cavale Blanche, Boulevard Tanguy Prigent, 29200 Brest, France. Electronic address: veronique.kerlan@chu-brest.fr.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Gouet</LastName>
<ForeName>Didier</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>CH La Rochelle, Diabetes Department, Rue du docteur Schweitzer, 17019 La Rochelle Cedex, France. Electronic address: didier.gouet@ch-larochelle.fr.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Perlemoine</LastName>
<ForeName>Caroline</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>CH Bretagne Sud, Diabetes Department, 5 Avenue Choiseul, 56322 Lorient, France. Electronic address: c.perlemoine@ch-bretagne-sud.fr.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ducluzeau</LastName>
<ForeName>Pierre-Henri</ForeName>
<Initials>PH</Initials>
<AffiliationInfo><Affiliation>CHU Tours, Diabetes Department, 2, boulevard Tonnellé, 37044 Tours cedex 9, France. Electronic address: ph.ducluzeau@chu-tours.fr.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Pichelin</LastName>
<ForeName>Matthieu</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>L'institut du thorax, CHU Nantes, INSERM CIC1413, Hôpital Nord Laennec Boulevard Jacques-Monod Saint-Herblain, 44093 Nantes Cedex 1, France. Electronic address: Matthieu.Pichelin@univ-nantes.fr.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ragot</LastName>
<ForeName>Stéphanie</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Clinical Investigation Center CIC1402, CHU de Poitiers 2 rue de la Miletrie, 86000 Poitiers, France. Electronic address: stephanie.ragot@univ-poitiers.fr.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Hadjadj</LastName>
<ForeName>Samy</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>Clinical Investigation Center CIC1402, CHU de Poitiers 2 rue de la Miletrie, 86000 Poitiers, France; CHU Poitiers, Diabetes Department, 2 rue de la Milétrie, CS 90577, 86000 Poitiers, France. Electronic address: samy.hadjadj@univ-nantes.fr.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Cariou</LastName>
<ForeName>Bertrand</ForeName>
<Initials>B</Initials>
<AffiliationInfo><Affiliation>L'institut du thorax, CHU Nantes, INSERM CIC1413, Hôpital Nord Laennec Boulevard Jacques-Monod Saint-Herblain, 44093 Nantes Cedex 1, France. Electronic address: bertrand.cariou@univ-nantes.fr.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Briet</LastName>
<ForeName>Claire</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>Institut MITOVASC, UMR CNRS 6015, INSERM 1083, Université d'Angers, 3 rue Roger Amsler, 49100 Angers, France; Diabetes Department, CHU d'Angers, 4 rue Larrey, 49100 Angers, France. Electronic address: claire.briet@chu-angers.fr.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><CollectiveName>VARDIA study group</CollectiveName>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
<ArticleDate DateType="Electronic"><Year>2019</Year>
<Month>12</Month>
<Day>19</Day>
</ArticleDate>
</Article>
<MedlineJournalInfo><Country>Ireland</Country>
<MedlineTA>Diabetes Res Clin Pract</MedlineTA>
<NlmUniqueID>8508335</NlmUniqueID>
<ISSNLinking>0168-8227</ISSNLinking>
</MedlineJournalInfo>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D003430" MajorTopicYN="N">Cross-Sectional Studies</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D003922" MajorTopicYN="N">Diabetes Mellitus, Type 1</DescriptorName>
<QualifierName UI="Q000150" MajorTopicYN="Y">complications</QualifierName>
<QualifierName UI="Q000523" MajorTopicYN="Y">psychology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005239" MajorTopicYN="N">Fear</DescriptorName>
<QualifierName UI="Q000523" MajorTopicYN="Y">psychology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007003" MajorTopicYN="N">Hypoglycemia</DescriptorName>
<QualifierName UI="Q000097" MajorTopicYN="Y">blood</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012893" MajorTopicYN="N">Sleep Wake Disorders</DescriptorName>
<QualifierName UI="Q000150" MajorTopicYN="Y">complications</QualifierName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">Anxiety-Depression</Keyword>
<Keyword MajorTopicYN="N">Fear of hypoglycaemia</Keyword>
<Keyword MajorTopicYN="N">Glycemic variability</Keyword>
<Keyword MajorTopicYN="N">Sleep disturbances</Keyword>
<Keyword MajorTopicYN="N">Type 1 diabetes mellitus</Keyword>
</KeywordList>
<CoiStatement>Declaration of Competing Interest The HFS-II is copyrighted and licensed through the University of Virginia. Licencing fees are used to support Dr. Gonder-Frederick's research on fear of hypoglycemia and related topics. S.H reports grants from ADAIRC and Dinno Santé, during the conduct of the study; personal fees and non-financial support from Astra Zeneca, personal fees and other from Bayer, Boehringer Ingelheim, Merck Sharpe Dome, Novonordisk, Sanofi, Servier and Eli Lilly, personal fees from Abbott DIAGNOSTICS, grants from Pierre Fabre Santé, outside the submitted work. B.C reports grants from Novo Nordsik, during the conduct of the study; personal fees from Abbott, Akcea, BMS, Genfi, Pierre Fabreand MSD, grants and personal fees from Amgen, Novo Nordsik, Regeneron and Sanofi, outside the submitted work.</CoiStatement>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="received"><Year>2019</Year>
<Month>09</Month>
<Day>16</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="revised"><Year>2019</Year>
<Month>12</Month>
<Day>06</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="accepted"><Year>2019</Year>
<Month>12</Month>
<Day>17</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2019</Year>
<Month>12</Month>
<Day>24</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2020</Year>
<Month>6</Month>
<Day>4</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>2019</Year>
<Month>12</Month>
<Day>24</Day>
<Hour>6</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">31866527</ArticleId>
<ArticleId IdType="pii">S0168-8227(19)31315-4</ArticleId>
<ArticleId IdType="doi">10.1016/j.diabres.2019.107988</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
<affiliations><list><country><li>France</li>
<li>États-Unis</li>
</country>
<region><li>Centre-Val de Loire</li>
<li>Nouvelle-Aquitaine</li>
<li>Pays de la Loire</li>
<li>Poitou-Charentes</li>
<li>Région Bretagne</li>
<li>Région Centre</li>
<li>Virginie</li>
</region>
<settlement><li>Angers</li>
<li>Brest</li>
<li>La Roche-sur-Yon</li>
<li>La Rochelle</li>
<li>Lorient</li>
<li>Nantes</li>
<li>Poitiers</li>
<li>Rennes</li>
<li>Tours</li>
</settlement>
<orgName><li>Université d'Angers</li>
</orgName>
</list>
<tree><country name="France"><region name="Pays de la Loire"><name sortKey="Suteau, Valentine" sort="Suteau, Valentine" uniqKey="Suteau V" first="Valentine" last="Suteau">Valentine Suteau</name>
</region>
<name sortKey="Allix, Ingrid" sort="Allix, Ingrid" uniqKey="Allix I" first="Ingrid" last="Allix">Ingrid Allix</name>
<name sortKey="Bonnet, Fabrice" sort="Bonnet, Fabrice" uniqKey="Bonnet F" first="Fabrice" last="Bonnet">Fabrice Bonnet</name>
<name sortKey="Briet, Claire" sort="Briet, Claire" uniqKey="Briet C" first="Claire" last="Briet">Claire Briet</name>
<name sortKey="Cariou, Bertrand" sort="Cariou, Bertrand" uniqKey="Cariou B" first="Bertrand" last="Cariou">Bertrand Cariou</name>
<name sortKey="Chaillous, Lucy" sort="Chaillous, Lucy" uniqKey="Chaillous L" first="Lucy" last="Chaillous">Lucy Chaillous</name>
<name sortKey="Delcourt Crespin, Ingrid" sort="Delcourt Crespin, Ingrid" uniqKey="Delcourt Crespin I" first="Ingrid" last="Delcourt Crespin">Ingrid Delcourt Crespin</name>
<name sortKey="Dubois, Severine" sort="Dubois, Severine" uniqKey="Dubois S" first="Séverine" last="Dubois">Séverine Dubois</name>
<name sortKey="Ducluzeau, Pierre Henri" sort="Ducluzeau, Pierre Henri" uniqKey="Ducluzeau P" first="Pierre-Henri" last="Ducluzeau">Pierre-Henri Ducluzeau</name>
<name sortKey="Fradet, Gerard" sort="Fradet, Gerard" uniqKey="Fradet G" first="Gerard" last="Fradet">Gerard Fradet</name>
<name sortKey="Gand, Elise" sort="Gand, Elise" uniqKey="Gand E" first="Elise" last="Gand">Elise Gand</name>
<name sortKey="Gouet, Didier" sort="Gouet, Didier" uniqKey="Gouet D" first="Didier" last="Gouet">Didier Gouet</name>
<name sortKey="Hadjadj, Samy" sort="Hadjadj, Samy" uniqKey="Hadjadj S" first="Samy" last="Hadjadj">Samy Hadjadj</name>
<name sortKey="Kerlan, Veronique" sort="Kerlan, Veronique" uniqKey="Kerlan V" first="Véronique" last="Kerlan">Véronique Kerlan</name>
<name sortKey="Leguerrier, Anne Marie" sort="Leguerrier, Anne Marie" uniqKey="Leguerrier A" first="Anne-Marie" last="Leguerrier">Anne-Marie Leguerrier</name>
<name sortKey="Perlemoine, Caroline" sort="Perlemoine, Caroline" uniqKey="Perlemoine C" first="Caroline" last="Perlemoine">Caroline Perlemoine</name>
<name sortKey="Pichelin, Matthieu" sort="Pichelin, Matthieu" uniqKey="Pichelin M" first="Matthieu" last="Pichelin">Matthieu Pichelin</name>
<name sortKey="Ragot, Stephanie" sort="Ragot, Stephanie" uniqKey="Ragot S" first="Stéphanie" last="Ragot">Stéphanie Ragot</name>
<name sortKey="Saulnier, Pierre Jean" sort="Saulnier, Pierre Jean" uniqKey="Saulnier P" first="Pierre-Jean" last="Saulnier">Pierre-Jean Saulnier</name>
<name sortKey="Wargny, Matthieu" sort="Wargny, Matthieu" uniqKey="Wargny M" first="Matthieu" last="Wargny">Matthieu Wargny</name>
</country>
<country name="États-Unis"><region name="Virginie"><name sortKey="Gonder Frederick, Linda" sort="Gonder Frederick, Linda" uniqKey="Gonder Frederick L" first="Linda" last="Gonder-Frederick">Linda Gonder-Frederick</name>
</region>
</country>
</tree>
</affiliations>
</record>

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Association between sleep disturbances, fear of hypoglycemia and psychological well-being in adults with type 1 diabetes mellitus, data from cross-sectional VARDIA study.

Association between sleep disturbances, fear of hypoglycemia and psychological well-being in adults with type 1 diabetes mellitus, data from cross-sectional VARDIA study.

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